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硒纳米技术与生物效应团队
何志军

时间:2025-04-22 作者: 来源: 阅读量:

何志军,男,中共党员,工学博士、博士后。长期围绕天然产物、钒和硒在生物医药、食品、保健领域应用的研究。第一作者和/或通讯作者身份在Chemical Engineering Journal、 Redox Biology、 Chinese Chemical Letters、Small Science、Phytomedicine 等本领域重要期刊发表SCI论文 17 篇

联系方式:hezhijun68@foxmail.com

教育/工作经历:

2022.12-至今, 讲师,武汉轻工大学

2020.09-2022.10,博士后,中科院长春应化所,化学

2014.09-2020.06,博士,深圳大学,光生物学 (硕博连读)

代表性学术论文:

1. Luo C, Xie F, Chen Q, Zhou J, He Z*, Cai J*. Starch-nanoencapsulated polyphenol-induced polysaccharide gel coatings with efficient preservation capability. Food Chemistry, 2025 1;467:142203.

2.  He Z, Li X, Yang Z, Liu X, Xie F, Lv X, Ni Z, Cheng S, Liu Q, Cai J. Self-assembly of selenium-loaded octenyl succinic anhydride-modified starch nanomicelles for treating inflammation-related brain diseases. Chemical Engineering Journal, 2024, 483: 149168.

3. He Z, Yang Q, Li X, Wang, Z, Wen, S, Dong M, Zhang W, Gong Y, Li Q, Dong H. Vanadium carbide quantum dots exert efficient anti-inflammatory effects in lipopolysaccharide-induced BV2 microglia and mice. Small Science, 2024, 4(10).

4. He Z, Zhang H, Li X, Shen L, Li N, Cheng S, Liu Q. Comparative proteomic analysis of cerebral cortex revealed neuroprotective mechanism of esculentoside A on Alzheimer's disease. European Journal of Pharmacology, 2024, 964: 176226.

5. He Z, Li X, Wang Z, Cao Y, Han S, Li N, Cai J, Cheng S, Liu Q. Protective effects of luteolin against amyloid beta-induced oxidative stress and mitochondrial impairments through peroxisome proliferator-activated receptor γ-dependent mechanism in Alzheimer's disease. Redox Biology, 2023, 66: 102848.

6. He Z, Li X, Zhang H, Liu X, Han S, Abdurahman A, Shen L, Du X, Li N, Yang D, Liu Q. A novel vanadium complex VO(p-dmada) inhibits neuroinflammation induced by lipopolysaccharide. Chinese Chemical Letters, 2023, 108236.

7. He Z, Zhang H, Li X, Tu S, Wang Z, Han S, Du X, Shen L, Li N, Liu Q. The protective effects of Esculentoside A through AMPK in the triple transgenic mouse model of Alzheimer's disease. Phytomedicine, 2023, 109: 154555.

8. He Z, Li X, Wang Z, Tu S, Feng J, Du X, Ni J, Li N, Liu Q. Esculentoside A alleviates cognitive deficits and amyloid pathology through peroxisome proliferator-activated receptor γ-dependent mechanism in an Alzheimer's disease model. Phytomedicine, 2022, 98: 153956.

9. He Z, Zheng L, Zhao X, Li X, Xue H, Zhao Q, Ren B, Li N, Ni J, Zhang Y, Liu Q. Adequate Supply of Bis(ethylmaltolato) oxidovanadium(IV) Remarkably Reversed the Pathological Hallmarks of Alzheimer's Disease in Triple-Transgenic Middle-Aged Mice. Biological Trace Element Research, 2022, 200(7): 3248-3264.

主持科研项目:

1. 湖北省自然科学基金,青年基金,基于巨噬细胞靶向淀粉/纳米硒胶束的自组装设计及其肠益生功效机制研究,2024AFB391,5万元,2024-2026;

2. 企业委托横向课题,安神健脑液对AD模型小鼠肠道稳态的调控及机制研究,89200783,9.9万元,2024-2025;

3. 武汉轻工大学博士启动金,新型纳米硒体系抑制淀粉样蛋白产生和内质网激干预阿尔茨海默病的作用机制,6万元,2023-2025;

4. 中国博士后科学基金会,面上资助,新型钒化合物防治阿尔茨海默症关于神经炎症的机理研究,2021M692210,8万元,2021-2022;

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