张绍鹏,男,汉族,中共党员。现任中西医结合学会-分子生药学专业委员会委员。主要从事药食植物以及药食真菌的应用基础研究,力图通过对生物活性成分的合成代谢网络的认识和发现,应用分子生物学和代谢工程的原理和技术,定向改造次生代谢途径,以期人工获得大量高价值的功效成分;同时对获得的天然产物进行药理学和免疫学研究。目前在《Genomics》《Front Microbiol》,《Int J Biol Macromol》,《Journal of Ethnopharmacology》,《Molecular Genetics and Genomics》,《Planta》,《Carbohydrate Polymers》,《Gene》,《Cell Immunol》,《中国中药杂志》,《中药材》,《生物技术通报》,《中药新药与临床药理》等国内外重要期刊发表论文30余篇,SCI收录20余篇,参编著作1部;授权国家发明专利4项。主持参与的国家自然科学基金项目2项,湖北省自然科学基金项目2项,湖北省教育厅项目2项,恩施州科技计划项目2项。
研究方向
1.药食植物的次生代谢产物合成调控的分子机制研究;
2.基于组学数据的生物信息学研究;
3.天然活性成分的药理功能研究;
4.基于食用菌活性成分的纳米硒制备和功能评价;
5.富硒功能农产品的开发和深加工研究
教育背景
副教授, 2013年-至今,武汉轻工大学,生物与制药工程学院
硕/博士,2005-2012年,华中农业大学,生命科学技术学院,作物遗传改良国家重点实验室。
访学, 2008年8-12,美国亚利桑那大学,BIO5研究中心, 生物芯片制作和数据分析技术。
学士, 2001-2005年,长江大学,生命科学技术学院 生物技术专业
代表论文
[1]Shaopeng Zhang, Hanyu Zheng, Rui Zhang, Menghua Shi, Ruifang Ren, Shuiyuan Cheng, and Chunyao Dun. Extraction optimization and antioxidant activity evaluation of se‐enriched walnut proteins. Journal of food processing and preservation. 2022, e16719. doi: 10.1111/jfpp.16719.
[2]Tian Zuo, Zuo Zhang, Peng Jiang, Rui Zhang, Danni Ni, Yuan Yuan,Shaopeng Zhang*. Characterization of chikusetsusaponin IV and V induced apoptosis in HepG2 cancer cells. Mol Biol Rep. 2022, 49(6):4247-4255. doi: 10.1007/s11033-022-07259-7.
[3]Zuo Zhang, Menghua Shi, Hanyu Zheng, Ruifang Ren,Shaopeng Zhang*, Xiaolong Ma*.Structural characterization and biological activities of a new polysaccharide isolated from Morchella Sextelata. Glycoconj J. 2022, 39(3):369-380. doi: 10.1007/s10719-022-10058-8.
[4]Shaopeng Zhang*, Guang Wang, Tian Zuo, Xiaohai Zhang, Ran Xu, Wenjun Zhua,Jingmao You, Rufeng Wang, Ping Chen. Comparative transcriptome analysis of rhizome nodes and internodes in Panax. japonicus var. major reveals candidate genes involved in the biosynthesis of triterpenoid saponins. Genomics. 2020, 112: 1112-1119.
[5]Shaopeng Zhang, Qihang Wu, Hang Lei, Hui Zheng, Fang Zhou, Zhanqiang Sun, Junwei Zhao, Xiaoli Yu*, Shulin Zhang*. Mannosylated structures of mycobacterial lipoarabinomannans facilitate the maturation and activation of dendritic cells. Cell Immunol. 2019,335:85-92.
[6] Ran Xu, Jia Song, Ying Zhang, Guang Wang,Shaopeng Zhang*. Genetic Diversity and Population structure of Chinese Panax japonicus C. A. Mey. Chinese Traditional Medicine Journal. 2018 1(1):1-9.
[7] Yayun Wua, Wenjun Zhu, Wei Wei, Xiaolong Zhao, Qi Wang,Wanyong Zeng, Yonglian Zheng, Ping Chen,Shaopeng Zhang*. De novo assembly and transcriptome analysis of sclerotial development in Wolfiporia cocos. Gene, 2016, 588:149-155.
[8]Shaopeng Zhang, Bingxiong Hu, Wei Wei, Ying Xiong, Wenjun Zhu, Fang Peng, Yang Yu, Yonglian Zheng, Ping Chen. De Novo Analysis of Wolfiporia cocos Transcriptome to Reveal the Differentially Expressed Carbohydrate-Active Enzymes (CAZymes) Genes During the Early Stage of Sclerotial Growth. Front Microbiol, 2016,7:83.
[9] Tao Yang,Shaopeng Zhang(co-first), Rufeng Wang, Danping Li, Yuanhua Hu, Jing Nie, Xiaolong Zhao, Qi Wang, Yan Chen, Yonglian Zheng, Ping Chen. Polysaccharides from Rhizoma Panacis Majoris and its anti-oxidant activity. Int J Biol Macromol. 2016, 86:756-763.
[10]Shaopeng Zhang, Yayun Wu, Jian Jin, Bingxiong Hu, Wanyong Zeng, Wenjun Zhu, Yonglian Zheng, Ping Chen. De novo Characterization of Panax japonicus C. A. Mey Transcriptome and Genes Related to Triterpenoid Saponin Biosynthesis. Biochemical and Biophysical Research Communications, 2015, 466: 450-455.
[11]Shaopeng Zhang, Rufeng Wang, Wanyong Zeng, Wenjun Zhu, Xifeng Zhang, Chong Wu, Jia Song, Yonglian Zheng, Ping Chen. Resource investigation of traditional medicinal plant Panax japonicus (T.Nees) C.A. Mey and its varieties in China. Journal of Ethnopharmacology, 2015, 166: 79-85.
[12]Shaopeng Zhang, Yannong Xiao, Jiuran Zhao, Fengge Wang, and Yonglian Zheng. Digital gene expression analysis of early root infection resistance to Sporisorium reilianum f.sp.zeae in maize. Molecular Genetics and Genomics, 2013, 288(1-2): 21-37.
[13]Shaopeng Zhang, Jack Gardiner, Yannong Xiao, Jiuran Zhao, Fengge Wang, Yonglian Zheng. Floral transition in maize infected with Sporisorium reilianum disrupts compatibility with this biotrophic fungal pathogen. Planta, 2013, 237(5): 1251-1266.
论著
郑用琏; 徐启江; 曲良焕; 闫达中; 胡南;张绍鹏. 基础分子生物学(第4版), 高等教育出版社, 600千字, 2021.
发明专利
1,一种茯苓NADPH氧化酶编码基因Nox及其应用,国家发明专利,专利号:ZL 2014 1 0487383.X
2,一种茯苓MAPK蛋白编码基因Smk1及其应用,国家发明专利,专利号:ZL 2014 1 0467727.0
3,一种野生竹节参无糖开放式组织培养快速育苗方法,国家发明专利,专利号:ZL 2015 1 0010242.3
4,一种珠子参β-香树素合酶基因及其应用,国家发明专利,专利号:ZL 20141 0474222.7
科研项目
1.国家自然科学基金项目
基于药用植物亲缘学的竹节参和珠子参药材关联性分析 2013.01-2016.12
2.国家“十三五”科技重大专项子课题
菌阴结核组合型分子标识及产品优化;2017/01-2020/12
3.中央本级重大增减支项目“名贵中药资源可持续利用能力建设项目”子课题
珠子参齐墩果烷型皂苷的糖基转移酶基因(UGT)的克隆和功能鉴定;2019/09-2021/12
4.湖北省自然科学基金项目
基因单核苷酸多态性(SNP)与竹节参遗传变异关系的研究 2018.1-2019.12
5.湖北省教育厅科学基金项目
竹节参皂苷IV和V对人肝癌HepG2细胞的作用机制研究 2018.1-2019.12
竹节参、珠子参和羽叶三七之间活性成分的差异性研究 2014.01-2016.12
获奖
2014-2015学年,武汉轻工大学 教学质量一等奖
2015-2016学年,武汉轻工大学 教学质量一等奖